Maple+Syrup+Urine+Disorder-Lexie

Maple Syrup Urine Disease (MSUD) MSUD is a potentially deadly disease if left untreated. Maple Syrup Urine Disease only occurs when your Leucine, isoleucine, and valine are not being used to break down proteins. When this happens in your body, the person with this disorder will have high levels of amino acids in their blood. This causes the cells od the brain to rapidly increase which also, may cause death. Any ad formations of the six subunits can be the starting point of MSUD.
 * Description: **

This disease is inherited in a autosomal recessive pattern. Order for the children to receive Maple Syrup Urine Disease, their parents both have to be carriers. If their parents are carriers, their children will have a twenty-five percent chance of getting the disease and/or fifty percent chance of being carriers of MSUD. Also, there is a twenty-five percent chance of the offspring being totally normal.
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The symptoms of this disease will begin at birth if this child inherited the disease. One of the first symptoms will occur in the first couple of days (3-4) of the baby being out in the real world. The baby might experience loss of appetite, fussiness, and the sweet smelling urine. The urine will smell similar to maple syrup. If you let this condition worsen over time, the baby may experience seizures, coma, and even die with in the few months of life.
 * Symptoms: **

In most states, they allow for the doctors to screen the baby for MSUD with in 24 hours of birth. Usually the doctors will withdraw blood from the baby’s heel of the foot, and then run tests for any signs of high leucine levels.
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MSUD patients must receive treatment at an very young age order for the patient to escape any sort of brain damage. Babies must have a special formula that do not contain any amino acids. As they grow older, they will always have to watch what they eat. They can not eat any foods with a lot of proteins in it. The doctors also can give them intravenous with a needle to lower the amino acids. In the future, they hope they can replace the bad gene that carries MSUD with a good gene; therefore, it will make a BCKD protein complex. (A normal complex)
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 * <span style="font-family: 'Times New Roman','serif'; font-size: 16px; line-height: 115%;">~ **<span style="font-family: 'Times New Roman','serif'; font-size: 16px; line-height: 115%;">The MSUD family support group

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 * <span style="font-family: 'Times New Roman','serif'; font-size: 16px; line-height: 115%;">List of sources: **