Adenosine+Deaminase+(ADA)+Deficiency-Urvish

Adenosine Deaminase (ADA) Deficiency Description: Adenosine Deaminase Deficiency is a severe combine deficiency disorder which is rare. ADA Deficiency is a disorder where the ADA proteins are not being produce. ADA proteins are used to break down a toxic called deoxyahenosine, which then builds up and begins destroying your immune cells. If you don’t have immune cells to fight off infections and germs, those germs could kill you.

Inheritance: ADA is an autosomal disorder located in chromosome 20. ADA is also a recessive, which means, unless the offspring has inherited both Bad chromosome 20s with ADA deficiency from his parents, he will have ADA deficiency; however, if he or she inherits only 1 bad chromosome 20 with ADA deficiency, ADA deficiency will not show itself.

Punnet Square:

Symptoms: Symptoms of ADA deficiency are infections of the skin, respiratory system, and gastrointestinal tract (stomach & intestine). This could also be caused by something other than ADA Deficiency so it is hard to tell whether you have ADA deficiency unless you get the proper tests

Diagnosed: There are 3 ways to test if you have ADA deficiency.
 * 1) If you are a girl, they could take a small tissue sample from the amniotic sac(place where the baby grows)
 * 2) Take a blood sample from the umbilical cord
 * 3) Take a blood sample from the offspring

Treatment: There are multiple ways to treat ADA deficiency but there is no cure yet.
 * 1) A bone marrow transplant from a healthy sibling
 * 2) <span style="font-family: 'Times New Roman',serif; font-size: 12pt;">Transfusion of red blood cell
 * 3) <span style="font-family: 'Times New Roman',serif; font-size: 12pt;">Injections of ADA enzymes
 * 4) <span style="font-family: 'Times New Roman',serif; font-size: 12pt;">Putting a normal ADA gene into immune cells

<span style="font-family: 'Times New Roman',serif; font-size: 12pt;">Interesting Facts:

media type="custom" key="9656762" <span style="font-family: 'Times New Roman',serif; font-size: 12pt;">Support Groups:
 * 1) <span style="font-family: 'Times New Roman',serif; font-size: 16px; line-height: 24px;">This disease if really rare.
 * 2) <span style="font-family: 'Times New Roman',serif; font-size: 12pt;">The first successful transfer of a normal ADA gene into immune cells was done in 1990.
 * 1) <span style="font-family: 'Times New Roman',serif; font-size: 12pt;">I HAVE ADENOSINE DEAMINASE DEFICIENCY @ <span style="color: black; font-family: 'Times New Roman',serif; font-size: 12pt;">[]

<span style="font-family: 'Times New Roman',serif; font-size: 12pt;">Sources:
 * 1) <span style="color: black; font-family: 'Times New Roman',serif; font-size: 12pt;">[]
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