MapleSyrupUrineDisease-Matt+Brennan

MSUD is a deadly disorder that affects the way the human body breaks down amino acids, leucine, isoleucine, and valine. When these amino acids aren’t being used, they can be recycled or broken down and used, they can be recycled or broken down and used for energy. Usually, they are broken down by six protein’s that work as a team and then form a complex that is called BCKD, or Branched-chain alpha- keto acid- dehydrogenase.
 * Description: **

**Inheritance: **MSUD is inherited in an autosomal recessive pattern.
 * Punnett Square: **

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 * Pedigree Chart:**

**Symptoms: **The symptoms of MSUD are loss of appetite, fussiness, and sweet-smelling urine.

**Diagnosis: **In some states, all babies are checked for MSUD within the first 24 hours after birth.

**Treatment: **Most of the MSUD treatments involve dietary restriction of the amino acids. The treatment must start very early to prevent damage to the brain. Babies with MSUD must eat a special formula that does not contain the 3 amino acids. As that infected person grows to adulthood, they always must watch their diet and avoid high protein foods, such as meat or eggs.

**I ****nteresting Facts: ** media type="custom" key="9658614" MSUD is and extremely rare disorder, only 1 in 180,000 babies are born with the disease known as MSUD. In certain populations, the disease is much more common. Among the Mennonites located in Pennsylvania, as many as 1 out of every 176 babies are born with MSUD. [] <span style="color: black; font-family: 'Times','serif'; font-size: 16px; line-height: 115%;">
 * <span style="color: black; font-family: 'Times','serif'; font-size: 16px; line-height: 115%;">Support Groups: **<span style="color: black; font-family: 'Times','serif'; font-size: 16px; line-height: 115%;">MSUD Family Support group.
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